Evaluación biológica del extracto de Muehlenbeckia tamnifolia (Kunth) Meisn fundamentado en el uso etnobotánico.

Abstract

Nowadays, ancestral knowledge has been the basis, to know certain parameters of plant species, which have characteristics that define biological activity, which could be of useful in modern medicine. The angoyuyo (Muehlenbeckia tamnifolia (Kunth) Meisn), stands out for being used in different Andean communities in Ecuador, for different ailments such as: inflammations, skin involvements and as disinfectant, among others. The objective posed was "Assess the biological action of Muehlenbeckia tamnifolia (Kunth) Meisn extract based on ethnobotanical use". The extract is based on the use of ethnobotanical, information obtained through a survey applied in ten markets of the Metropolitan District of Quito. The biological evaluation of the extract was performed using the method of Microdilution in broth against the strains of Escherichia coli ATCC® 25922, Staphylococcus aureus ATCC® 25923 and Candida albicans ATCC 10231 strains, confirmed through the Kirby-Bauer test. Better reporting of the dry hydroalcoholic extract of Muehlenbeckia tamnifolia (Kunth) Meisn, due to the identified a higher number of concentrations that exhibited biological activity, determining that the most sensitive microorganism is Staphylococcus aureus ATCC 25923, its highest inhibition rate is 40 %. Concluding that the angoyuyo species used in the hydroalcoholic extract obtained by percolation presents antimicrobial activity against Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 25923 and antifungal activity against Candida albicans ATCC 10231.