Capacidad antioxidante en una crema y un gel elaborados a base de extractos hidroalcohólicos y eutécticos profundos de solanum nigrum l

Abstract

Among the plant species of wide medicinal use is Solanum nigrum Linn, belonging to the Solanaceae family, known as "Hierba Mora", it is a plant native to America All parts of this plant are used in traditional medicine as a treatment for various diseases, especially cough, fever, asthma, skin diseases, gastric system and liver problems, these properties are attributed to its chemical compounds: alkaloids, flavonoids, tannins, saponins, glycosides, proteins, carbohydrates, coumarins and phytosterols. This specimen is of interest to the cosmetics industry, due to its various neutralization mechanisms of reactive oxygen species (ROS), which are caused by endogenous factors of metabolism and also by exogenous factors, such as exposure to: sunlight, computers; that trigger premature aging in the population. In the present study, phenolic compounds were extracted from S. nigrum Linn in hydroalcoholic and deep eutectic extracts macerated for 72 and 168 hours, in 96° ethanol, citric acid: glucose, in a 1:1 molar ratio, citric acid: glucose: fructose:water, in a 1:1:1:9 molar ratio, citric acid: betaine: water in a 1:1:1 ratio and betaine: glycerin: water in a 1:2:1 ratio with an additional 5% water; evaluating the inhibitory capacity of the extracts by the chemical method of 2,2-diphenyl-1-picrylhydrazyl (DPPH). Subsequently, antioxidant formulations of a cosmetic cream and gel were developed using the extracts at a concentration of 2, 5 and 10%. It was determined that all the extracts and formulations have an inhibitory capacity for DPPH radicals, but it was greater in the eutectic extract of Betaine: glycerin: water, since it inhibited 24.92% of the DPPH radicals in the gel and 18.95% of the DPPH radicals. In the cream This raises the possibility that the cosmetic industry could consider eutectic solvents to replace traditional solvents, as a healthy alternative for the population and friendly to the environment.