Análisis del incremento de la producción de una planta farmacéutica utilizando herramientas de la metodología lean manufacturing en el área de mantenimieto.

Abstract

In our country the pharmaceutical industry is limited for many reasons, however, over the years it is essential that locally produced drugs must be effective, reasonably priced to the consumer and profitable for the producer since the health assurance in the population is an unavoidable condition. Consequently, the present work focuses on the study of three basic tools of the Lean methodology (5'S, Standardization, TPM) that can be applied to the maintenance department of a pharmaceutical company, to obtain as a result a percentage increase in the productivity of the company with the decrease or elimination, if possible, of unscheduled stops, improvement of the maintainability processes, optimization of resources, and decrease of defective product. Chapter 1 contains all the necessary theoretical framework on the methodology of the three tools mentioned above, their application, history, benefits that each of the tools provides; there is also an explanatory fragment on the regulatory bodies of the pharmaceutical industry and the degree of influence that the GMP standards have on it. In chapter 2, an initial survey of the available physical and structural resources in the company is carried out, then an analysis of the current state of the maintenance department in terms of the plant is shown, then an existing problematic production line is analyzed in order to analyze the circumstances and improve its process. In chapter 3 we proceed to analyze the expected results of the research with the definition of achievable goals over time, as well as the establishment of the values of the proposed goals to achieve the expected results. of the proposed goal values to keep control over the process of continuous improvement of the department in general. Finally, the conclusions of the study are explained, the advantages to be acquired with the use of the tools mentioned in this work and a specific recommendation that allows to VI continue with the cycle of continuous improvement within the same environment of its application for a future diffusion on the other existing areas of the company that allows to viralize the Lean thinking in the whole company. In the Annexes section you can find application formats of the tools explained in the research, the formats presented can serve as guides, but the Lean methodology is very flexible and can be adapted to the specific situation of each organization.