Evaluación de la actividad biológica de los extractos hidroalcohólicos de VASCONCELLEA PARVIFLORA ubicada en el campus María Auxiliadora de la Universidad Politécnica Salesiana

Abstract

The species Vasconcellea parviflora (fosforillo), present in the tropical dry forest, is characterized by presenting unique colors in its morphology. The objective of this research study was to carry out phytochemical screening to qualitatively observe secondary metabolites in the leaf, stem, root and evaluate the biological activity of the Vasconcellea parviflora plant, using methodologies such as DPPH for antioxidant activity and micro dilution for antimicrobial activity. The secondary metabolites identified in the phytochemical screening test of all the samples of hydroalcoholic extracts and ethyl acetate found were alkaloids, flavonoids, flavones, aurones, coumarins and carbohydrates, observing better results in the hydroalcoholic extracts. For the quantification of antioxidants, the DPPH assay was used and using a Trolox solution as a standard, a value of 0.48 mmol Trolox/g was obtained, which indicates moderate to high antioxidant activity, which means that Vasconcellea parviflora is a potential natural source. of antioxidants, while the biological activity was determined by the minimum inhibitory concentration (MCI) of the plant extracts in bacterial inoculum of Escherichia coli ATTC 8739 using the microdilution technique, obtaining a low antimicrobial activity in the ethyl acetate extracts corresponding to leaf and root with an inhibition percentage of 58% and 40%. In conclusion, studies carried out on the species Vasconcellea parviflora indicate its potential use in biotechnological applications.