Estudio de factibilidad para el control del tamaño de partícula en un comprimido antiinflamatorio

Abstract

The current work proposal aims to determine the optimal particle size percentages for the Ketorolac Tromethamine 30 mg tablets product using the mechanical sieving method. The evaluation was carried out in the process prior to compression using the Six Sigma approach and statistical tools, with the goal of identifying alternatives that allow reducing waste percentages, determining the different mesh sizes required, and verifying if the analysis results vary when applying the proposed improvements. Finally, recommendations are made to improve the process and final product in terms of anti-inflammatory tablets to guarantee their quality and minimize economic losses.